Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.
Identifieur interne : 000859 ( Main/Corpus ); précédent : 000858; suivant : 000860Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.
Auteurs : R G Brown ; C D Marsden ; N. Quinn ; M A WykeSource :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 1984-05.
Abstract
Sixteen patients with idiopathic Parkinson's disease were selected who were all showing severe fluctuations in motor function ("on-off" phenomenon). Measures of cognitive function and of subjective affect/arousal state were taken on two occasions, once when "on" and once when "off". Twenty-five matched normal controls were also assessed on the same measures. Results revealed, on the average, a drop in cognitive function plus an adverse swing in affect/arousal state, in the patient group in the "off" condition, compared to the levels when "on". Analysis of the data suggested that the main factor associated with cognitive function when "off" was not the severity of disability but the level of affect/arousal. The fluctuations in cognitive function found tended to be mild relative to the severe changes in motor ability, and were present in only a proportion of patients.
Url:
DOI: 10.1136/jnnp.47.5.454
Links to Exploration step
ISTEX:E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title><author><name sortKey="Brown, R G" sort="Brown, R G" uniqKey="Brown R" first="R G" last="Brown">R G Brown</name></author><author><name sortKey="Marsden, C D" sort="Marsden, C D" uniqKey="Marsden C" first="C D" last="Marsden">C D Marsden</name></author><author><name sortKey="Quinn, N" sort="Quinn, N" uniqKey="Quinn N" first="N" last="Quinn">N. Quinn</name></author><author><name sortKey="Wyke, M A" sort="Wyke, M A" uniqKey="Wyke M" first="M A" last="Wyke">M A Wyke</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00</idno><date when="1984-05-01" year="1984">1984-05-01</date><idno type="doi">10.1136/jnnp.47.5.454</idno><idno type="url">https://api.istex.fr/document/E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00/fulltext/pdf</idno><idno type="wicri:Area/Main/Corpus">000859</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title><author><name sortKey="Brown, R G" sort="Brown, R G" uniqKey="Brown R" first="R G" last="Brown">R G Brown</name></author><author><name sortKey="Marsden, C D" sort="Marsden, C D" uniqKey="Marsden C" first="C D" last="Marsden">C D Marsden</name></author><author><name sortKey="Quinn, N" sort="Quinn, N" uniqKey="Quinn N" first="N" last="Quinn">N. Quinn</name></author><author><name sortKey="Wyke, M A" sort="Wyke, M A" uniqKey="Wyke M" first="M A" last="Wyke">M A Wyke</name></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="1984-05">1984-05</date><biblScope unit="volume">47</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="454">454</biblScope></imprint><idno type="ISSN">0022-3050</idno></series><idno type="istex">E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00</idno><idno type="DOI">10.1136/jnnp.47.5.454</idno><idno type="href">jnnp-47-454.pdf</idno><idno type="PMID">6736975</idno><idno type="local">jnnp;47/5/454</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Sixteen patients with idiopathic Parkinson's disease were selected who were all showing severe fluctuations in motor function ("on-off" phenomenon). Measures of cognitive function and of subjective affect/arousal state were taken on two occasions, once when "on" and once when "off". Twenty-five matched normal controls were also assessed on the same measures. Results revealed, on the average, a drop in cognitive function plus an adverse swing in affect/arousal state, in the patient group in the "off" condition, compared to the levels when "on". Analysis of the data suggested that the main factor associated with cognitive function when "off" was not the severity of disability but the level of affect/arousal. The fluctuations in cognitive function found tended to be mild relative to the severe changes in motor ability, and were present in only a proportion of patients.</div></front></TEI><istex><corpusName>bmj</corpusName><author><json:item><name>R G Brown</name></json:item><json:item><name>C D Marsden</name></json:item><json:item><name>N Quinn</name></json:item><json:item><name>M A Wyke</name></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Research Article</value></json:item></subject><language><json:string>eng</json:string></language><abstract>Sixteen patients with idiopathic Parkinson's disease were selected who were all showing severe fluctuations in motor function ("on-off" phenomenon). Measures of cognitive function and of subjective affect/arousal state were taken on two occasions, once when "on" and once when "off". Twenty-five matched normal controls were also assessed on the same measures. Results revealed, on the average, a drop in cognitive function plus an adverse swing in affect/arousal state, in the patient group in the "off" condition, compared to the levels when "on". Analysis of the data suggested that the main factor associated with cognitive function when "off" was not the severity of disability but the level of affect/arousal. The fluctuations in cognitive function found tended to be mild relative to the severe changes in motor ability, and were present in only a proportion of patients.</abstract><qualityIndicators><score>6.62</score><pdfVersion>1.3</pdfVersion><pdfPageSize>525.12 x 694.56 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>1</keywordCount><abstractCharCount>878</abstractCharCount><pdfWordCount>6458</pdfWordCount><pdfCharCount>41138</pdfCharCount><pdfPageCount>12</pdfPageCount><abstractWordCount>135</abstractWordCount></qualityIndicators><title>Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title><pmid><json:string>6736975</json:string></pmid><genre><json:string>research-article</json:string></genre><host><volume>47</volume><pages><first>454</first></pages><issn><json:string>0022-3050</json:string></issn><issue>5</issue><genre></genre><language><json:string>unknown</json:string></language><eissn><json:string>1468-330X</json:string></eissn><title>Journal of Neurology, Neurosurgery & Psychiatry</title></host><publicationDate>1984</publicationDate><doi><json:string>10.1136/jnnp.47.5.454</json:string></doi><id>E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00</id><fulltext><json:item><original>true</original><mimetype>application/pdf</mimetype><extension>pdf</extension><uri>https://api.istex.fr/document/E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00/fulltext/pdf</uri></json:item><json:item><original>false</original><mimetype>application/zip</mimetype><extension>zip</extension><uri>https://api.istex.fr/document/E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title><respStmt xml:id="ISTEX-API" resp="Références bibliographiques récupérées via GROBID" name="ISTEX-API (INIST-CNRS)"></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>BMJ Publishing Group Ltd</publisher><availability><p>BMJ</p></availability><date>1984-05-01</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title><author><persName><forename type="first">R G</forename><surname>Brown</surname></persName></author><author><persName><forename type="first">C D</forename><surname>Marsden</surname></persName></author><author><persName><forename type="first">N</forename><surname>Quinn</surname></persName></author><author><persName><forename type="first">M A</forename><surname>Wyke</surname></persName></author></analytic><monogr><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="pISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="1984-05"></date><biblScope unit="volume">47</biblScope><biblScope unit="issue">5</biblScope><biblScope unit="page" from="454">454</biblScope></imprint></monogr><idno type="istex">E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00</idno><idno type="DOI">10.1136/jnnp.47.5.454</idno><idno type="href">jnnp-47-454.pdf</idno><idno type="PMID">6736975</idno><idno type="local">jnnp;47/5/454</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1984-05-01</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Sixteen patients with idiopathic Parkinson's disease were selected who were all showing severe fluctuations in motor function ("on-off" phenomenon). Measures of cognitive function and of subjective affect/arousal state were taken on two occasions, once when "on" and once when "off". Twenty-five matched normal controls were also assessed on the same measures. Results revealed, on the average, a drop in cognitive function plus an adverse swing in affect/arousal state, in the patient group in the "off" condition, compared to the levels when "on". Analysis of the data suggested that the main factor associated with cognitive function when "off" was not the severity of disability but the level of affect/arousal. The fluctuations in cognitive function found tended to be mild relative to the severe changes in motor ability, and were present in only a proportion of patients.</p></abstract></profileDesc><revisionDesc><change when="1984-05-01">Created</change><change when="1984-05">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-3-14">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><original>false</original><mimetype>text/plain</mimetype><extension>txt</extension><uri>https://api.istex.fr/document/E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus bmj" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="no"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" URI="archivearticle.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article" xml:lang="EN"><front><journal-meta><journal-id journal-id-type="hwp">jnnp</journal-id><journal-id journal-id-type="nlm-ta">J Neurol Neurosurg Psychiatry</journal-id><journal-title>Journal of Neurology, Neurosurgery & Psychiatry</journal-title><abbrev-journal-title abbrev-type="publisher">J Neurol Neurosurg Psychiatry</abbrev-journal-title><issn pub-type="ppub">0022-3050</issn><issn pub-type="epub">1468-330X</issn><publisher><publisher-name>BMJ Publishing Group Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">6736975</article-id><article-id pub-id-type="other">jnnp;47/5/454</article-id><article-id pub-id-type="doi">10.1136/jnnp.47.5.454</article-id><article-id pub-id-type="other">454</article-id><article-id pub-id-type="other">jnnp.47.5.454</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Brown</surname><given-names>R G</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Marsden</surname><given-names>C D</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Quinn</surname><given-names>N</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Wyke</surname><given-names>M A</given-names></name></contrib></contrib-group><pub-date pub-type="ppub"><month>5</month><year>1984</year></pub-date><pub-date pub-type="epub"><day>1</day><month>5</month><year>1984</year></pub-date><volume>47</volume><volume-id pub-id-type="other">47</volume-id><volume-id pub-id-type="other">47</volume-id><issue>5</issue><issue-id pub-id-type="other">jnnp;47/5</issue-id><issue-id pub-id-type="other">5</issue-id><issue-id pub-id-type="other">47/5</issue-id><fpage>454</fpage><self-uri content-type="pdf" xlink:role="full-text" xlink:href="jnnp-47-454.pdf"></self-uri><abstract><p>Sixteen patients with idiopathic Parkinson's disease were selected who were all showing severe fluctuations in motor function ("on-off" phenomenon). Measures of cognitive function and of subjective affect/arousal state were taken on two occasions, once when "on" and once when "off". Twenty-five matched normal controls were also assessed on the same measures. Results revealed, on the average, a drop in cognitive function plus an adverse swing in affect/arousal state, in the patient group in the "off" condition, compared to the levels when "on". Analysis of the data suggested that the main factor associated with cognitive function when "off" was not the severity of disability but the level of affect/arousal. The fluctuations in cognitive function found tended to be mild relative to the severe changes in motor ability, and were present in only a proportion of patients.</p></abstract></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.</title></titleInfo><name type="personal"><namePart type="given">R G</namePart><namePart type="family">Brown</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C D</namePart><namePart type="family">Marsden</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">N</namePart><namePart type="family">Quinn</namePart><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M A</namePart><namePart type="family">Wyke</namePart><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><originInfo><publisher>BMJ Publishing Group Ltd</publisher><dateIssued encoding="w3cdtf">1984-05</dateIssued><dateCreated encoding="w3cdtf">1984-05-01</dateCreated></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Sixteen patients with idiopathic Parkinson's disease were selected who were all showing severe fluctuations in motor function ("on-off" phenomenon). Measures of cognitive function and of subjective affect/arousal state were taken on two occasions, once when "on" and once when "off". Twenty-five matched normal controls were also assessed on the same measures. Results revealed, on the average, a drop in cognitive function plus an adverse swing in affect/arousal state, in the patient group in the "off" condition, compared to the levels when "on". Analysis of the data suggested that the main factor associated with cognitive function when "off" was not the severity of disability but the level of affect/arousal. The fluctuations in cognitive function found tended to be mild relative to the severe changes in motor ability, and were present in only a proportion of patients.</abstract><relatedItem type="host"><titleInfo><title>Journal of Neurology, Neurosurgery & Psychiatry</title></titleInfo><titleInfo type="abbreviated"><title>J Neurol Neurosurg Psychiatry</title></titleInfo><genre type="Journal">journal</genre><identifier type="ISSN">0022-3050</identifier><identifier type="eISSN">1468-330X</identifier><identifier type="PublisherID-hwp">jnnp</identifier><identifier type="PublisherID-nlm-ta">J Neurol Neurosurg Psychiatry</identifier><part><date>1984</date><detail type="volume"><caption>vol.</caption><number>47</number></detail><detail type="issue"><caption>no.</caption><number>5</number></detail><extent unit="pages"><start>454</start></extent></part></relatedItem><identifier type="istex">E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00</identifier><identifier type="DOI">10.1136/jnnp.47.5.454</identifier><identifier type="href">jnnp-47-454.pdf</identifier><identifier type="PMID">6736975</identifier><identifier type="local">jnnp;47/5/454</identifier><recordInfo><recordContentSource>BMJ</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonV1/Data/Main/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000859 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Corpus/biblio.hfd -nk 000859 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonV1
|flux= Main
|étape= Corpus
|type= RBID
|clé= ISTEX:E19D4DCE7C0867F42D6F2FE3C8F6079D6B587B00
|texte= Alterations in cognitive performance and affect-arousal state during fluctuations in motor function in Parkinson's disease.
}}
| This area was generated with Dilib version V0.6.23. |  |